Extracellular Vesicles Derived From Mesenchymal Stem Cells (MSC) in Regenerative Medicine: Applications in Skin Wound Healing.
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Extracellular Vesicles Derived From Mesenchymal Stem Cells (MSC) in Regenerative Medicine: Applications in Skin Wound Healing.
The cells secrete extracellular vesicles (EV) which probably has its origins endosomal, or from evaginations of the plasma membrane. The former is usually called exosomes, with sizes ranging from 50 to 100 nm. This EV-containing lipid bilayer membrane protein associated with. Molecules such as nucleic acids (DNA, mRNA, miRNA, lncRNA, etc.) and proteins can be stored inside. EV composition depending on the type of producer cells and physiological conditions.
Through them, the cells and the microenvironment modifying the behavior of neighboring cells. That is done by transferring factors that modulate different metabolic and signaling pathways. Due to their nature, the EV can be applied as a diagnostic and therapeutic tool in medicine. Mesenchymal stromal cells (MSC) have immunomodulatory properties and high regenerative capacity. These features are associated with the activity and EV paracrine secretion. Therefore, the study of exosomes produced by MSC has intensified for use in regenerative medicine cell-free. In this area, the use of EV for the treatment of chronic skin ulcers (CSU) has been proposed.
The injury occurs when the normal healing did not finish well. It is usually due to excessive extension of the inflammatory phase. These ulcers associated with aging and disease, such as diabetes, so that their prevalence increases with one of these latter diseases, especially in developed countries. It has a socio-economic impact is very important. In this review, we show that the application of the MSC-derived EV for the treatment of CSU have a positive effect, including speeding up healing and reduce scar formation. This is because the EV has immunosuppressive properties and immunomodulatory.
Likewise, they have the ability to activate angiogenesis, proliferation, migration, and differentiation of the major cell types involved in the regeneration of the skin. They include endothelial cells, fibroblasts, and keratinocytes. Most studies conducted so far preclinical. Therefore, there is a need to promote a deeper knowledge of the conditions of production, isolation, and mechanisms of action EV. Interestingly, their potential applications in the treatment of CSU opens the door to the design of new therapeutic strategies are highly effective.
Extracellular Vesicles Derived From Mesenchymal Stem Cells (MSC) in Regenerative Medicine: Applications in Skin Wound Healing.
comparative advantage infrapatellar fat pad: a source of stem cells for regenerative medicine emerging.
Growing evidence suggests that the infrapatellar fat pad (IPFP) -derived stem cells (IPFSCs) exert a strong proliferative capacity and multilineage differentiation potential. However, some paper summarizes the advantages that IPFP and IPFSCs have in regenerative medicine. In this review, we describe the development and anatomy IPFP by comparing it with the adjacent fibrous tissue, synovium, and more often harvested fat depot, subcutaneous adipose tissue.
In addition, we explore the similarities and differences stem cells from three of these networks in terms IPFSCs, stem cells synovium-derived and stem cell tissue derived subcutaneous adipose in proliferative capacity and tri-lineage differentiation potential, including chondrogenesis, osteogenesis and adipogenesis ,
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human P-glycoprotein . This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody for detection of P-glycoprotein 1 from Human, Mouse, Rat. This P-glycoprotein 1 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human P-glycoprotein 1
Description: A polyclonal antibody for detection of P-glycoprotein 1 from Human, Mouse, Rat. This P-glycoprotein 1 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human P-glycoprotein 1
Description: A polyclonal antibody for detection of P-glycoprotein 1 from Human, Mouse, Rat. This P-glycoprotein 1 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human P-glycoprotein 1
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is unconjugated.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Alkaline Phosphatase.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to APC .
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to APC/Cy7.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Biotin.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Dylight 350.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Dylight 405.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Dylight 488.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Dylight 594.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Dylight 633.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to FITC.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to HRP.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to PE/ATTO 594.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to PerCP.
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to RPE .
Description: A polyclonal antibody for P Glycoprotein from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human P Glycoprotein 1?MDR1?. The Antibody is tested and validated for IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:200). This P Glycoprotein antibody is conjugated to Streptavidin.
Description: A sandwich ELISA for quantitative measurement of Porcine permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Porcine permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Porcine permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Canine permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Canine permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Canine permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rabbit permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rabbit permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rabbit permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Goat permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Goat permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Goat permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rat permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rat permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rat permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Human permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Human permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Human permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Monkey permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Monkey permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Monkey permeability glycoprotein, P-gp in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: Quantitative sandwich ELISA for measuring Mouse Permeability glycoprotein (P-gp) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Permeability glycoprotein (P-gp)
Description: Quantitative sandwich ELISA for measuring Mouse Permeability glycoprotein (P-gp) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Permeability glycoprotein (P-gp)
Description: Quantitative sandwich ELISA for measuring Mouse Permeability glycoprotein (P-gp) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human P-GP (Permeability Glycoprotein)
Description: A sandwich ELISA kit for quantitative measurement of Human P-GP (Permeability Glycoprotein) in samples from Serum, Plasma, Cell supernatant
CLIA kit for Human P-GP (Permeability Glycoprotein)
Description: A sandwich CLIA kit for quantitative measurement of Human P-GP (Permeability Glycoprotein) in samples from Serum, Plasma, Cell supernatant
Finally, we highlight the advantages of IPFSCs in regenerative medicine, such as abundant accessibility and ability to resist inflammation and aging, two hurdles for cell-based tissue regeneration. Given the comparative advantage of IPFSCs, which IPFP can serve as a source of stem cells for regenerative medicine is very good, especially for the regeneration of cartilage.
