Prospect of Stem Cell Therapy and Regenerative Medicine in Osteoporosis

The field of cell therapy and regenerative medicine could hold the promise of restoring normal tissue structure and function. In addition, the main target of stem cell-based therapies is the chronic disease and disability for life without certain drugs such as osteoporosis.

Osteoporosis as one of the important causes of morbidity in older men and post-menopausal women is characterized by reduced quantity of bone or atrophy of bone tissue that leads to increased risk of osteoporotic fractures. A common treatment method for osteoporosis can only prevent the loss of bone mass and bone recover partially.

However, stem cell-based therapy is considered as a new approach to the regeneration of bone tissue. Here, the mesenchymal stem cells as an important candidate for the purpose of regenerative medicine especially the regeneration of bone is a common type of most of the cells with anti-inflammatory potential of the immune-privileged, and worry less ethical than other types of stem cells are investigated in osteoporosis. Based on the findings, the effectiveness of the mesenchymal stem cells close to a large extent dependent on their secretory function. Indeed, they could be involved in the formation of normal bone remodeling through the initiation of a specific molecular signaling pathway.

Thus, the purpose here is to review the effect of stem cell-based therapies in osteoporosis.
Special edition of “Stem Cells and Regenerative Medicine” enthusiastic released by the editorial board of the European Journal of histochemistry in 2020. The fusion of these two topics reflect the expectations and potential that advances in regenerative medicine will be the promising results from basic and translational research collected in this special issue , This issue is dedicated to identifying priorities in stem cell biology and catch the latest thinking in stem cell-based regenerative medicine.

Prospect of Stem Cell Therapy and Regenerative Medicine in Osteoporosis
Prospect of Stem Cell Therapy and Regenerative Medicine in Osteoporosis

the additional role of mesenchymal stem cells as regenerative medicine army to weaken the inflammatory process of severe acute respiratory tract infection caused by COVID-19

Acute respiratory infections as one of the most common problems of the health system can also be considered as an important reason for the worldwide morbidity and mortality from infectious diseases. Coronavirus is a well-known group of respiratory viruses that can cause acute respiratory infections.

In current conditions, the new coronavirus cited 2019 as the worldwide agent for the respiratory system problems. According to the investigation, people with old age and the underlying disease are at higher risk than 2019 new coronavirus infection. Indeed, they might indicate a severe form of the disease (severe acute respiratory infection).

Based on the promising role of cell therapy and regenerative medicine approaches in the treatment of life-threatening diseases, it seems to apply a cell-based approach can also be a strategy hopes to raise the subject with severe acute respiratory tract infection caused by a new coronavirus 2019. Here, because of the amazing effects of mesenchymal stem cells in the treatment of various diseases, this review focuses on the additional role of mesenchymal stem cells to decrease the acute inflammatory process of respiratory infections caused by respiratory infections Novel coronavirus.

hCG Holo Antibody

V3064-20UG 20 ug
EUR 186.15
Description: This mAb reacts only with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG mAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.

hCG Holo Antibody

V3064IHC-7ML 7 ml
EUR 424.15
Description: This mAb reacts only with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG mAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.

hCG Holo Antibody

V3064SAF-100UG 100 ug
EUR 424.15
Description: This mAb reacts only with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG mAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Human Holo Transferrin

22060355-1 500 mg
EUR 365.12

Human Holo Transferrin

G599 100mg
EUR 195

Transferrin (Holo) Human

GWB-28A17E 10 g Ask for price

Human Holo Transferrin

7-05365 500mg Ask for price

Human Holo Transferrin

7-05366 1gram Ask for price

Human Holo Transferrin

7-05367 5grams Ask for price

Bovine Holo Transferrin

7-05368 500mg Ask for price

Bovine Holo Transferrin

7-05369 1gram Ask for price

Bovine Holo Transferrin

7-05370 5grams Ask for price

Lactoferrin protein (Holo)

30-1147 1 g
EUR 394.8
Description: Purified recombinant Human Lactoferrin protein

Transferrin protein (Holo)

30-1224 100 mg
EUR 263
Description: Purified native Human Transferrin Holo protein

Transferrin protein (Holo)

30R-AT020 10 gram Ask for price
Description: Purified native Human Transferrin protein (Holo)

Lactoferrin Holo Protein

20-abx262996
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  • 100 mg
  • 10 mg

Lactoferrin Holo Protein

abx262996-1gr 1 gr
EUR 1062

Holo Transferrin Peptide

abx260005-1gr 1 gr
EUR 777.6

Holo Transferrin Peptide

abx260005-500mg 500 mg
EUR 560.4

Holo Transferrin Peptide

abx260005-5grs 5 grs
EUR 2498.4

CG Holo c3 Antibody

GWB-191EB5 0.25 mg Ask for price

CG Holo c2 Antibody

GWB-CA40CF 0.25 mg Ask for price

Bovine Transferrin, holo (>98%)

TF21-N-10 10 mg
EUR 196.8

Cow Holo Transferrin Protein

abx260048-1gr 1 gr
EUR 927.6

Cow Holo Transferrin Protein

abx260048-500mg 500 mg
EUR 627.6

Cow Holo Transferrin Protein

abx260048-5grs 5 grs
EUR 3700.8

holo-Transferrin from Human

34443-44 100MG
EUR 113.4

Transferrin (HOLO), Human Plasma

7542-100 each
EUR 196.8

Transferrin (HOLO), Human Plasma

7542-500 each
EUR 385.2

Holo TC ELISA KIT|Human

EF010957 96 Tests
EUR 826.8

Recombinant Human Lactoferrin Holo

7-05518 10mg Ask for price

Recombinant Human Lactoferrin Holo

7-05519 100mg Ask for price

Recombinant Human Lactoferrin Holo

7-05520 1gram Ask for price

Human Holo TC(Holotranscobalamin) ELISA Kit

ELK0720-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human Holo TC protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Holo TC. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Holo TC in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Holo TC(Holotranscobalamin) ELISA Kit

ELK0720-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human Holo TC protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Holo TC. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Holo TC in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Holotranscobalamin (Holo TC) Elisa Kit

EK714978 96 Wells
EUR 0.51

Human Holo TC(Holotranscobalamin) ELISA Kit

EKF58231-48T 48T
EUR 396.9

Human Holo TC(Holotranscobalamin) ELISA Kit

EKF58231-5x96T 5x96T
EUR 2693.25

Human Holo TC(Holotranscobalamin) ELISA Kit

EKF58231-96T 96T
EUR 567

Human Holo TC(Holotranscobalamin) ELISA Kit

EH4163 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.094 ng/ml

Human Holo TC (Holotranscobalamin) ELISA Kit

SL3623Hu 96 Tests
EUR 468

Human Holotranscobalamin(Holo TC) ELISA Kit

YLA3803HU-48T 48T Ask for price

Human Holotranscobalamin(Holo TC) ELISA Kit

YLA3803HU-96T 96T Ask for price

Mouse Holotranscobalamin(Holo TC) ELISA Kit

YLA1804MO-48T 48T Ask for price

Mouse Holotranscobalamin(Holo TC) ELISA Kit

YLA1804MO-96T 96T Ask for price

hCG (HOLO C3 Epitope) Antibody

GWB-DE186E 0.5 mg Ask for price

OPPA01582-10MG - LTF Holo Protein

OPPA01582-10MG 10mg
EUR 70

HTF Holo Transferrin Human protein

PROTP02787 Regular: 1g
EUR 692.4
Description: Human Holo Transferrin is a glycoprotein of approximately 77 kDa containing 679 amino acids.

HTF Holo Transferrin Bovine protein

PROTQ29443 Regular: 1g
EUR 818.4
Description: Bovine Holo Transferrin is a glycoprotein of approximately 80 kDa.

Mouse Anti Hcg Holo Monoclonal Antibody

CABT-49228MH 0.5 mg
EUR 858

Human Holo-tanscobalmine(HTC) ELISA Kit

QY-E05534 96T
EUR 433.2

Transferrin, Holo, Human Plasma, purified >97%

TF25-N-BLK blk Ask for price

Human Holo-Transcobalmine, HTC GENLISA ELISA

KBH4161 1 x 96 wells
EUR 286

LTF Lactoferrin Holo Human Recombinant Protein

PROTP02788 Regular: 100mg
EUR 380.4
Description: Recombinant Human Holo Lactoferrin produced in Plant is a glycosylated mature polypeptide sequence without signal 1-19 peptide, chain 20-712 AA. Having an approximate molecular mass of 77-80 kDa.;The Human Holo Lactotransferrin is purified by proprietary chromatographic techniques.

OPPA01402-500MG - HTF - Holo Transferrin Protein

OPPA01402-500MG 500mg
EUR 556

Holo-[acyl-Carrier-Protein] Synthase (acpS) Antibody

20-abx300313
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  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mouse Anti Hcg (Holo C3 Epitope) Monoclonal Antibody

CABT-49221MH 0.5 mg
EUR 858

Purified Human Holo-Transferrin Protein WB +ve Control

TF11-C 100 ul
EUR 343.2

Recombinant Human LTF Holo Protein, Untagged, Rice-10mg

QP12596-10mg 10mg
EUR 186

Holo-[Acyl-Carrier-Protein] Synthase (ACPS) Antibody (HRP)

20-abx300314
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  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Human LTF Holo Protein, Untagged, Rice-100mg

QP12596-100mg 100mg
EUR 241.2

Recombinant Human LTF Holo Protein, Untagged, Rice-1gram

QP12596-1gram 1gram
EUR 795.6

Holo-[Acyl-Carrier-Protein] Synthase (ACPS) Antibody (FITC)

20-abx300315
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  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

OPPA01231-500MG - HTF Human - Human Holo Transferrin Protein

OPPA01231-500MG 500mg
EUR 416

Holo-[Acyl-Carrier-Protein] Synthase (ACPS) Antibody (Biotin)

20-abx300316
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Staphylococcus aureus Holo-[acyl-carrier-protein] synthase (acpS)

1-CSB-EP740005SKV
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  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Staphylococcus aureus Holo-[acyl-carrier-protein] synthase(acpS) expressed in E.coli

Anti-HCG Holo (Pregnancy & Choriocarcinoma Marker) Monoclonal Antibody

M00739-1 100ug/vial
EUR 476.4
Description: Mouse Monoclonal HCG Holo (Pregnancy & Choriocarcinoma Marker) Antibody. Validated in IHC and tested in Human.

hCG Holo (Pregnancy & Choriocarcinoma Marker); Clone HCGab/52 (Concentrate)

RA0399-C.1 0.1 ml
EUR 60.07

hCG Holo (Pregnancy & Choriocarcinoma Marker); Clone HCGab/52 (Concentrate)

RA0399-C.5 0.5 ml
EUR 200.66

Recombinant Staphylococcus aureus Holo-[acyl-carrier-protein] synthase (acpS)

CSB-EP740005SKV 4043 mg Ask for price

Recombinant Staphylococcus aureus Holo-[acyl-carrier-protein] synthase(acpS)

AP73773 1mg
EUR 2826

FSH

E8EM170417 100ul
EUR 275
Description: Available in various conjugation types.

FSH

E8EM170418 100ul
EUR 275
Description: Available in various conjugation types.

FSH

DE1288 96
EUR 95

FSH

hor-249 100IU
EUR 100
Description: Human Follicle Stimulating Hormone

FSH

hor-253 2µg
EUR 60
Description: Recombinant Human Follicle Stimulating Hormone

FSH

GWB-F537BF 1x96 Assays Ask for price

Recombinant Acholeplasma laidlawii Holo-[acyl-carrier-protein] synthase (acpS)

CSB-EP431428ATX 3539 mg Ask for price

Recombinant Acholeplasma laidlawii Holo-[acyl-carrier-protein] synthase (acpS)

RPC27202-100ug 100ug
EUR 801.9

Recombinant Acholeplasma laidlawii Holo-[acyl-carrier-protein] synthase (acpS)

RPC27202-1mg 1mg
EUR 2885.2

Recombinant Acholeplasma laidlawii Holo-[acyl-carrier-protein] synthase (acpS)

RPC27202-20ug 20ug
EUR 448.1

Monoclonal HCG Holo (Pregnancy & Choriocarcinoma Marker) Antibody, Clone: HCGab/52

APR07356G 7 ml
EUR 580.8
Description: A Monoclonal antibody against Human HCG Holo (Pregnancy & Choriocarcinoma Marker). The antibodies are raised in Mouse and are from clone HCGab/52. This antibody is applicable in IHC

Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

1-CSB-YP669769SBAF
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  • Ask for price
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  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase(acpS) expressed in Yeast

Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

1-CSB-EP669769SBAF
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  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase(acpS) expressed in E.coli

Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

1-CSB-BP669769SBAF
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase(acpS) expressed in Baculovirus

Cytochrome C (CYCS) (Holo) mouse monoclonal antibody, clone 2CYZ-702, Purified

AM00175PU-N 100 µg Ask for price

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

CSB-YP669769SBAF 6529 mg Ask for price

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

CSB-EP669769SBAF 3890 mg Ask for price

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

CSB-BP669769SBAF 205 mg Ask for price

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

RPC26343-100ug 100ug
EUR 1463

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

RPC26343-20ug 20ug
EUR 633.6

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

RPC25810-100ug 100ug
EUR 721.6

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

RPC25810-1mg 1mg
EUR 2884.7

Recombinant Streptococcus pyogenes serotype M28 Holo-[acyl-carrier-protein] synthase (acpS)

RPC25810-20ug 20ug
EUR 448.1

FSH, human

4781-1000 each
EUR 2526

FSH, human

4781-50 each
EUR 405.6

FSH ELISA

E22-HC9008 96T
EUR 395

Recombinant Streptococcus agalactiae serotype III Holo-[acyl-carrier-protein] synthase (acpS)

CSB-EP352442SMH 6792 mg Ask for price

FSH protein

30-1109 1 mg Ask for price
Description: Purified native Human FSH protein

FSH protein

30-1953 50 IU
EUR 250
Description: Partially pure FSH protein

FSH protein

30R-2707 50 ug
EUR 382
Description: Purified native Human FSH protein

FSH Protein

30R-3425 1 mg
EUR 2600
Description: Human Follicle-stimulating hormone

Buffalo(FSH)

QY-E60079 96T
EUR 511.2

FSH antibody

10-F15A 1 mg
EUR 154
Description: Mouse monoclonal FSH antibody

FSH antibody

10-F15B 1 mg Ask for price
Description: Mouse monoclonal FSH antibody

FSH antibody

10-F15C 1 mg
EUR 1603
Description: Mouse monoclonal FSH antibody

FSH antibody

10-F15D 1 mg Ask for price
Description: Mouse monoclonal FSH antibody

FSH antibody

10-2380 500 ug
EUR 277
Description: Mouse Monoclonal FSH antibody

FSH antibody

10-2381 500 ug
EUR 360
Description: Mouse Monoclonal FSH antibody

FSH antibody

10-2382 500 ug
EUR 277
Description: Mouse Monoclonal FSH antibody

FSH antibody

10-7978 1 mg
EUR 304
Description: Mouse monoclonal FSH antibody

FSH antibody

10-7979 1 mg
EUR 257
Description: Mouse monoclonal FSH antibody

FSH antibody

10C-CR2109M2 1 mg Ask for price
Description: Mouse monoclonal FSH antibody

FSH antibody

10C-CR2109M3 1 mg
EUR 195
Description: Mouse monoclonal FSH antibody

FSH antibody

10C-CR2109M4 1 mg
EUR 195
Description: Mouse monoclonal FSH antibody

FSH antibody

20-FG10 1 ml
EUR 205
Description: Goat polyclonal FSH antibody

FSH antibody

20-FR10S 1 ml
EUR 95
Description: Rabbit polyclonal FSH antibody

FSH receptor

E8ER1909-08 100ul
EUR 275
Description: Available in various conjugation types.

FSH Antibody

GWB-28D862 1 mg Ask for price

FSH Antibody

GWB-298C92 0.5 mg Ask for price

FSH Antibody

GWB-2AB356 0.25 mg Ask for price

FSH Antibody

GWB-101A9D 1 mg Ask for price

FSH Antibody

GWB-3FC239 1 mg Ask for price

FSH antibody

70-XR52 1 mg
EUR 195
Description: Rabbit polyclonal Human FSH antibody

FSH Antibody

GWB-AED466 1 mg Ask for price

FSH Antibody

GWB-E5AAB0 0.1 mg Ask for price

FSH Antibody

GWB-7F531C 1 mg Ask for price

FSH Antibody

GWB-8F60D0 1 mg Ask for price

FSH Antibody

GWB-F94B00 0.1 ml Ask for price

FSH RECEPTOR

GWB-C97AFF 0.05 mg Ask for price

FSH Antibody

GWB-B9F690 0.5 ml Ask for price

FSH Antibody

P1043-01m 0.1m
EUR 181.2

FSH Antibody

P1043-1ml 1ml
EUR 398.4

Human recombinant (>97%) holo lactoferrin (For cell culture, low endotoxin, >95%, animal free)

LTF17-R-100 100 mg
EUR 270

hCG beta (CGB3) (Holo C3 epitope) mouse monoclonal antibody, clone INN-hCG-45, Purified

SM2109P 500 µg Ask for price

hCG beta (CGB3) (Holo C2 epitope) mouse monoclonal antibody, clone INN-hCG-53, Purified

SM2124P 500 µg Ask for price

Recombinant S. aureus Holo-[acyl-carrier-protein] synthase Protein, His-SUMO, E.coli-10ug

QP7737-ec-10ug 10ug
EUR 391.2

Recombinant S. aureus Holo-[acyl-carrier-protein] synthase Protein, His-SUMO, E.coli-1mg

QP7737-ec-1mg 1mg
EUR 2763.6

Recombinant S. aureus Holo-[acyl-carrier-protein] synthase Protein, His-SUMO, E.coli-50ug

QP7737-ec-50ug 50ug
EUR 522

Recombinant S. aureus Holo-[acyl-carrier-protein] synthase Protein, His-SUMO, E.coli-100ug

QP7737-ec-100ug 100ug
EUR 848.4

Recombinant S. aureus Holo-[acyl-carrier-protein] synthase Protein, His-SUMO, E.coli-200ug

QP7737-ec-200ug 200ug
EUR 1338

Acute 2019 as one of the problems of the most public health system can also be considered as an important reason for the worldwide morbidity and mortality from infectious diseases. Coronavirus is a well-known group of respiratory viruses that can cause acute respiratory infections. In current conditions, the new coronavirus cited 2019 as the worldwide agent for the respiratory system problems.